Guillermo Velasco was born in Madrid, studied Biology and
obtained his PhD degree (1997) at the School of Biology of the Complutense
University, Madrid, Spain. After defending his PhD, he got an EMBO long-term
fellowship to work in Philip Cohen’s laboratory at the MRC Protein
Phosphorylation Unit (Dundee, Scotland) on a project aimed at studying the
regulation and of the Rho-activated protein kinase (ROCK).
On the year 1999 he got a position as Assistant
Teacher at the School of Chemistry of the Complutense University
and since the year 2003 he is Associated professor of the
Department of Biochemistry and Molecular Biology I.
On the year 2001 he started a line of research
aimed at investigating the mechanisms underlying cannabinoid
antitumoral action as well as at optimizing the potential
clinical utilization of these agents in cancer therapies.
lines of research in his group are currently investigating the
role of endoplasmic reticulum stress, autophagy, apoptosis,
intracellular trafficking of ceramide and regulation of mTORC1
and mTORC2 in cannabinoid antitumoral action as well as the
participation of growth factor receptor-activated pathways in
the resistance to the antineoplasic actions of cannabinoids.